Association of IL-6 G-174C (rs1800795) variant with the susceptibility to hepatocellular carcinoma in patients with chronic hepatitis.

doi:10.1186/s43046-024-00238-y

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Association of IL-6 G-174C (rs1800795) variant with the susceptibility to hepatocellular carcinoma in patients with chronic hepatitis.

Journal of the Egyptian National Cancer Institute - 21 Oct 2024

Abuelnadar Eman H, Ramadan Lamiaa M, Shahin Hanaa Elsayed, Alakilli Saleha Y M, Wahsh Eman, El-Beltagy Nanis S, Salem Eman T, Hatata Abdelrahman S, El-Said Afaf M, Alhelf Maha

Abstract excerpt

AIM: An ineffective immune response resulting from dysregulation of cytokine production might encourage viral persistence and cause chronic viral hepatitis to worsen. This study examined the relationship between alterations in interleukin-6 (IL-6) levels and the IL-6 - 174 G > C (rs1800795) polymorphism, as well as how this polymorphism affects the development and progression of chronic hepatitis brought on by...

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PMID: 39428452
DOI: 10.1186/s43046-024-00238-y
PMCID: PMC13313833

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