Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole Genome and Transcriptome Sequencing of Two Multi-Drug Resistant Mycobacterium tuberculosis Strains to Facilitate Illustrating Their Virulence in vivo.

Frontiers in cellular and infection microbiology - 1 Jan 2020

Tang Jun, Liu Zhihao, Shi Ya'nan, Zhan Lingjun, Qin Chuan

Abstract excerpt

Mycobacterium tuberculosis clinical strains usually possess traits different from the laboratory strains like H37Rv, especially those clinical drug resistant strains. With whole genome and transcriptome sequencing, we depicted the feature of two multi-drug resistant Mtb strains in resistance and virulence. Compared with H37Rv, the differential expressed genes (DEGs) of the MDR strains showed featured enrichment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice
Share to Mycobacterium research and diagnosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mycobacterium tuberculosis

Share to Pharmaceutical Preparations

Share to Phenotype

Share to Transcriptome

Share to Tuberculosis Research and Epidemiology

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 32500039
DOI: 10.3389/fcimb.2020.00219
PMCID: PMC7242654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole Genome and Transcriptome Sequencing of Two Multi-Drug Resistant Mycobacterium tuberculosis Strains to Facilitate Illustrating Their Virulence in vivo.PMID 32500039Read ↗

Alterations in molecular response of Mycobacterium tuberculosis against anti-tuberculosis drugs.Semantic proximity Read ↗

Whole Genome Sequencing and Metabolomic Profiling of Six Clinical Mycobacterium Tuberculosis Isolates Reveal Drug Resistance-Associated Features.Semantic proximity Read ↗

Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targetsSemantic proximity Read ↗

Close Related Drug-Resistance Beijing Isolates of Mycobacterium tuberculosis Reveal a Different Transcriptomic Signature in a Murine Disease Progression Model.Semantic proximity Read ↗

A genome-wide analysis of multidrug-resistant and extensively drug-resistant strains of Mycobacterium tuberculosis Beijing genotype.Semantic proximity Read ↗

Whole genome sequencing and global metabolome profiling of clinical <i>Mycobacterium tuberculosis</i> isolates provide insights to their drug resistance statusSemantic proximity Read ↗

Mycobacterium tuberculosis strains exhibit differential and strain-specific molecular signatures in pulmonary epithelial cells.Semantic proximity Read ↗

Gene expression analysis of two extensively drug-resistant tuberculosis isolates show that two-component response systems enhance drug resistance.Semantic proximity Read ↗

Rifampicin-induced transcriptome response in rifampicin-resistant Mycobacterium tuberculosis.Semantic proximity Read ↗

Adaptive gene profiling of Mycobacterium tuberculosis during sub-lethal kanamycin exposure.Semantic proximity Read ↗

Genome analyses of 174 strains of Mycobacterium tuberculosis provide insight into the evolution of drug resistance and reveal potential drug targets.Semantic proximity Read ↗

Pangenome Reconstruction of Mycobacterium tuberculosis as a Guide to Reveal Genomic Features Associated with Strain Clinical PhenotypeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.