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Gene expression analysis of two extensively drug-resistant tuberculosis isolates show that two-component response systems enhance drug resistance.

Tuberculosis (Edinburgh, Scotland) - 1 May 2015

Yu Guohua, Cui Zhenling, Sun Xian, Peng Jinfu, Jiang Jun, Wu Wei, Huang Wenhua, Chu Kaili, Zhang Lu, Ge Baoxue, Li Yao

Abstract excerpt

Global analysis of expression profiles using DNA microarrays was performed between a reference strain H37Rv and two clinical extensively drug-resistant isolates in response to three anti-tuberculosis drug exposures (isoniazid, capreomycin, and rifampicin). A deep analysis was then conducted using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 25869645
DOI: 10.1016/j.tube.2015.03.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25869645-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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