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Interactive effect of MTHFR C677T polymorphism and sex on symptoms and cognitive functions in Chinese patients with chronic schizophrenia.

Aging - 4 Jun 2020

Gao Jie, Xiu Mei Hong, Liu Dian Ying, Wei Chang Wei, Zhang Xiangyang

Abstract excerpt

The etiology of schizophrenia is still unknown, and the MTHFR gene has been shown to be associated with SCZ. Previous studies have shown that patients with schizophrenia exhibit sex differences in symptoms and cognitive function. However, no study has been conducted to investigate the sex difference in the association between C677T polymorphism and symptoms and cognitive impairment in Chinese patients with...

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PMID: 32497019
DOI: 10.18632/aging.103248
PMCID: PMC7346048

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