Article
AGK‐BRAF is associated with distant metastasis and younger age in pediatric papillary thyroid carcinoma
29 Mar 2019
Abstract excerpt
BACKGROUND: The incidence of thyroid carcinoma has increased in most populations, including pediatric patients. The increase is almost exclusively due to an increase in the incidence of papillary thyroid carcinoma (PTC). Genetic alterations leading to mitogen-activated protein kinase (MAPK) pathway activation are highly prevalent in PTC, with BRAF V600E mutation being the most common event in adult PTC. Although...
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