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Article

Chronic HCV Infection Is Associated with Overexpression of Human Endogenous Retroviruses that Persists after Drug-Induced Viral Clearance.

International journal of molecular sciences - 1 Jun 2020

Tovo Pier-Angelo, Garazzino Silvia, Daprà Valentina, Alliaudi Carla, Silvestro Erika, Calvi Cristina, Montanari Paola, Galliano Ilaria, Bergallo Massimiliano

Abstract excerpt

Chronic hepatitis C virus (HCV) infection is associated with several hepatic and extrahepatic complications, including cancers and autoimmune disorders, whose frequency is reduced but not abolished after drug-induced viral clearance. The causes of these complications and of their persistence are ill-defined. Human endogenous retroviruses (HERVs) are remnants of ancestral infections and constitute 8% of the human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32492928
DOI: 10.3390/ijms21113980
PMCID: PMC7313012

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