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Cancer Precursor Syndromes and Their Detection in the Head and Neck.

Hematology/oncology clinics of North America - 1 Aug 2024

Villa Alessandro, William William N, Hanna Glenn J

Abstract excerpt

This article explores the multifaceted landscape of oral cancer precursor syndromes. Hereditary disorders like dyskeratosis congenita and Fanconi anemia increase the risk of malignancy. Oral potentially malignant disorders, notably leukoplakia, are discussed as precursors influenced by genetic and immunologic facets. Molecular insights delve into genetic mutations, allelic imbalances, and immune modulation as key...

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Genetic Predisposition to Disease
Head and Neck Neoplasms
Leukoplakia, Oral
Mouth Neoplasms
Precancerous Conditions

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PMID: 38705773
DOI: 10.1016/j.hoc.2024.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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