Article
Molecular basis of ALS and FTD: implications for translational studies.
Arhiv za higijenu rada i toksikologiju - 1 Dec 2015
Liščić Rajka M
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative disorders, related by signs of deteriorating motor and cognitive functions, and short survival. The cause is unknown and no effective treatment currently exists. For ALS, there is only a drug Riluzole and a promising substance arimoclomol. The overlap between ALS and FTD occurs at clinical, genetic, and pathological...
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