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Article

Frontotemporal Lobar Degeneration: Mechanisms and Therapeutic Strategies.

Molecular neurobiology - 1 Nov 2016

Li Ya-Qing, Tan Meng-Shan, Yu Jin-Tai, Tan Lan

Abstract excerpt

Frontotemporal lobar degeneration (FTLD) is characterized by progressive deterioration of frontal and anterior temporal lobes of the brain and often exhibits frontotemporal dementia (FTD) on clinic, in <65-year-old patients at the time of diagnosis. Interdisciplinary approaches combining genetics, molecular and cell biology, and laboratory animal science have revealed some of its potential molecular mechanisms....

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PMID: 26537902
DOI: 10.1007/s12035-015-9507-5

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