Article
Frontotemporal dementia: from genetics to therapeutic approaches.
Expert opinion on investigational drugs - 1 Jun 2024
Buccellato Francesca R, D'Anca Marianna, Tartaglia Gianluca Martino, Del Fabbro Massimo, Galimberti Daniela
Abstract excerpt
INTRODUCTION: Frontotemporal dementia (FTD) includes a group of neurodegenerative diseases characterized clinically by behavioral disturbances and by neurodegeneration of brain anterior temporal and frontal lobes, leading to atrophy. Apart from symptomatic treatments, there is, at present, no disease-modifying cure for FTD. AREAS COVERED: Three main mutations are known as causes of familial FTD, and large...
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