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Article

TERC Variants Associated with Short Leukocyte Telomeres: Implication of Higher Early Life Leukocyte Telomere Attrition as Assessed by the Blood-and-Muscle Model.

Cells - 31 May 2020

Toupance Simon, Stathopoulou Maria G, Petrelis Alexandros M, Gorenjak Vesna, Labat Carlos, Lai Tsung-Po, Visvikis-Siest Sophie, Benetos Athanase

Abstract excerpt

Short leukocyte telomere length (LTL) is associated with atherosclerotic cardiovascular disease (ASCVD). Mendelian randomisation studies, using single nucleotide polymorphisms (SNPs) associated with short LTL, infer a causal role of LTL in ASCVD. Recent results, using the blood-and-muscle model, indicate that higher early life LTL attrition, as estimated by the ratio between LTL and skeletal muscle telomere...

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Identifiers

PMID: 32486379
DOI: 10.3390/cells9061360
PMCID: PMC7349705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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