Article
Telomere-associated polymorphisms correlate with cardiovascular disease mortality in Caucasian women: the Cardiovascular Health Study.
Mechanisms of ageing and development - 1 May 2012
Burnett-Hartman Andrea N, Fitzpatrick Annette L, Kronmal Richard A, Psaty Bruce M, Jenny Nancy S, Bis Josh C, Tracy Russ P, Kimura Masayuki, Aviv Abraham
Abstract excerpt
Leukocyte telomere length (LTL) is linked to cardiovascular disease (CVD); however, it is unclear if LTL has an etiologic role in CVD. To gain insight into the LTL and CVD relationship, a cohort study of CVD mortality and single nucleotide polymorphisms (SNPs) in OBFC1 and TERC, genes related to LTL, was conducted among 3271 Caucasian participants ages ≥65 years enrolled 1989-1990 in the Cardiovascular Health...
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