A unifying model for the propagation of prion proteins in yeast brings insight into the [PSI+] prion.

Abstract excerpt

The use of yeast systems to study the propagation of prions and amyloids has emerged as a crucial aspect of the global endeavor to understand those mechanisms. Yeast prion systems are intrinsically multi-scale: the molecular chemical processes are indeed coupled to the cellular processes of cell growth and division to influence phenotypical traits, observable at the scale of colonies. We introduce a novel...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amyloid
• Share to Computer Simulation
• Share to Guanidine