Article
Correlation between the expression of folate receptor alpha (FRα) and clinicopathological features in patients with lung adenocarcinoma.
Lung cancer (Amsterdam, Netherlands) - 1 Jul 2020
Tamura Nobumasa, Fujiwara Yutaka, Hashimoto Taiki, Shiraishi Hideaki, Kitano Shigehisa, Shimizu Toshio, Kuwano Kazuyoshi, Yamamoto Noboru, Motoi Noriko
Abstract excerpt
OBJECTIVES: Folate receptor alpha (FRα) is expressed on the cell surface, mediates its intracellular transport via receptor-mediated endocytosis, and is involved in cell division. Whether FRα could be a potential therapeutic target in FRα-expressing cancers remains unknown. Here, we retrospectively investigated the correlations between tumor FRα expression in lung adenocarcinoma (LADC) and clinicopathological...
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