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Article

A Rapid and Accurate Detection Approach for Multidrug-Resistant Tuberculosis Based on PCR-ELISA Microplate Hybridization Assay.

Laboratory medicine - 2 Nov 2020

Zhou Ye-Cheng, He Shu-Mei, Wen Zi-Lu, Zhao Jun-Wei, Song Yan-Zheng, Zhang Ying, Zhang Shu-Lin

Abstract excerpt

Rapid and accurate diagnosis of multidrug-resistant tuberculosis (MDR-TB) is important for timely and appropriate therapy. In this study, a rapid and easy-to-perform molecular test that integrated polymerase chain reaction (PCR) amplification and a specific 96-well microplate hybridization assay, called PCR-ELISA (enzyme-linked immunosorbent assay), were developed for detection of mutations in rpoB, katG, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32447387
DOI: 10.1093/labmed/lmaa016

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