Article
Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism.
Cells - 18 May 2020
Lefort Charlotte, Roumain Martin, Van Hul Matthias, Rastelli Marialetizia, Manco Rita, Leclercq Isabelle, Delzenne Nathalie M, Marzo Vincenzo Di, Flamand Nicolas, Luquet Serge, Silvestri Cristoforo, Muccioli Giulio G, Cani Patrice D
Abstract excerpt
Diverse metabolic disorders have been associated with an alteration of N-acylethanolamine (NAE) levels. These bioactive lipids are synthesized mainly by N-acylphosphatidylethanolamine-selective phospholipase D (NAPE-PLD) and influence host metabolism. We have previously discovered that NAPE-PLD in the intestine and adipose tissue is connected to the pathophysiology of obesity. However, the physiological function...
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