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Article

Global dynamics of healthy and cancer cells competing in the hematopoietic system.

Mathematical biosciences - 1 Aug 2020

Andersen Morten, Hasselbalch Hans C, Kjær Lasse, Skov Vibe, Ottesen Johnny T

Abstract excerpt

Stem cells in the bone marrow differentiate to ultimately become mature, functioning blood cells through a tightly regulated process (hematopoiesis) including a stem cell niche interaction and feedback through the immune system. Mutations in a hematopoietic stem cell can create a cancer stem cell leading to a less controlled production of malfunctioning cells in the hematopoietic system. This was mathematically...

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Identifiers

PMID: 32442449
DOI: 10.1016/j.mbs.2020.108372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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