Article
Classical and Alternative Activation of Rat Microglia Treated with Ultrapure Porphyromonas gingivalis Lipopolysaccharide In Vitro.
Toxins - 19 May 2020
Memedovski Zylfi, Czerwonka Evan, Han Jin, Mayer Joshua, Luce Margaret, Klemm Lucas C, Hall Mary L, Mayer Alejandro M S
Abstract excerpt
The possible relationship between periodontal disease resulting from the infection of gingival tissue by the Gram-negative bacterium Porphyromonas gingivalis (P. gingivalis) and the development of neuroinflammation remains under investigation. Recently, P. gingivalis lipopolysaccharide (LPS) was reported in the human brain, thus suggesting it might activate brain microglia, a cell type participating in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.