Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypermutation in single-stranded DNA.

DNA repair - 1 Jan 2000

Saini Natalie, Gordenin Dmitry A

Abstract excerpt

Regions of genomic DNA can become single-stranded in the course of normal replication and transcription as well as during DNA repair. Abnormal repair and replication intermediates can contain large stretches of persistent single-stranded DNA, which is extremely vulnerable to DNA damaging agents and hypermutation. Since such single-stranded DNA spans only a fraction of the genome at a given instance, hypermutation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteria
Share to DNA, Single-Stranded
Share to Eukaryota

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutagenesis

Share to Mutation

Share to Neoplasms

Share to Telomere

Share to Viruses

Source

Open in PubMed Open full text

Identifiers

PMID: 32438271
DOI: 10.1016/j.dnarep.2020.102868
PMCID: PMC7234795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypermutation in single-stranded DNA.PMID 32438271Read ↗

Damage-induced localized hypermutability.Semantic proximity Read ↗

Echoed induction of nucleotide variants and chromosomal structural variants in cancer cells.Semantic proximity Read ↗

Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.Semantic proximity Read ↗

Causes of genome instability.Semantic proximity Read ↗

Causes and consequences of DNA single-strand breaksSemantic proximity Read ↗

Mutating for Good: DNA Damage Responses During Somatic HypermutationSemantic proximity Read ↗

Genomic landscape of radiation-induced somatic mutations in a normal cell.Semantic proximity Read ↗

From RNA World to SARS-CoV-2: The Edited Story of RNA Viral Evolution.Semantic proximity Read ↗

Endogenous DNA Damage as a Source of Genomic Instability in Cancer.Semantic proximity Read ↗

Triplex DNA and human diseaseSemantic proximity Read ↗

Clusters of Multiple Mutations: Incidence and Molecular Mechanisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.