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Article

The Neandertal Progesterone Receptor.

Molecular biology and evolution - 1 Sept 2020

Zeberg Hugo, Kelso Janet, Pääbo Svante

Abstract excerpt

The hormone progesterone is important for preparing the uterine lining for egg implantation and for maintaining the early stages of pregnancy. The gene encoding the progesterone receptor (PGR) carries introgressed Neandertal haplotypes with two missense substitutions and a mobile Alu element. These Neandertal gene variants have reached nearly 20% frequency in non-Africans and have been associated with preterm...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32437543
DOI: 10.1093/molbev/msaa119
PMCID: PMC7475037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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