Article

Progesterone: An Enigmatic Ligand for the Mineralocorticoid Receptor

2020-01-21

Abstract excerpt

The progesterone receptor (PR) mediates progesterone regulation of female reproductive physiology, as well as gene transcription in non-reproductive tissues, such as brain, bone, lung and vasculature, in both women and men. An unusual property of progesterone is its high affinity for the mineralocorticoid receptor (MR), which regulates electrolyte transport in the kidney in humans and other terrestrial vertebrates...

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Literature Corpus work: 12bf49f3-b40d-594b-be97-c2d7f017fef6
DOI: 10.20944/preprints202001.0231.v1

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