Article
Association between polymorphisms in the progesterone receptor gene and endometriosis.
Molecular human reproduction - 1 Sept 2005
Treloar Susan A, Zhao Zhen Zhen, Armitage Trudi, Duffy David L, Wicks Jacqueline, O'Connor Daniel T, Martin Nicholas G, Montgomery Grant W
Abstract excerpt
The progesterone receptor (PR) is a candidate gene for the development of endometriosis, a complex disease with strong hormonal features, common in women of reproductive age. We typed the 306 base pair Alu insertion (AluIns) polymorphism in intron G of PR in 101 individuals, estimated linkage disequilibrium (LD) between five single-nucleotide polymorphisms (SNPs) across the PR locus in 980 Australian triads...
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