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Article

Impedimetric Sensing of Factor V Leiden Mutation by Zip Nucleic Acid Probe and Electrochemical Array.

Biosensors - 7 Sept 2020

Erdem Arzum, Eksin Ece

Abstract excerpt

A carbon nanofiber enriched 8-channel screen-printed electrochemical array was used for the impedimetric detection of SNP related to Factor V Leiden (FV Leiden) mutation, which is the most common inherited form of thrombophilia. FV Leiden mutation sensing was carried out in three steps: solution-phase nucleic acid hybridization between zip nucleic acid probe (Z-probe) and mutant type DNA target, followed by the...

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PMID: 32906640
DOI: 10.3390/bios10090116
PMCID: PMC7559847

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