Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Triple signal biosensing platform for ultrasensitive and wide-range detection of HLA gene targets.

Analytical methods : advancing methods and applications - 18 Sept 2025

Ma Li, Qi Liqin, Ke Sujie, Zeng Feihui, Liu Deying, Liu Xiaoying, Wang Lijing, Liu Libin

Abstract excerpt

Hyperthyroidism, a multifaceted endocrine disorder, is strongly associated with specific human leukocyte antigen (HLA) alleles, which also play a critical role in drug-induced complications such as agranulocytosis. Conventional HLA genotyping methods often face limitations in simultaneously achieving high accuracy, rapidity, and operational simplicity. To address these challenges, we developed a multimodal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Biosensing Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorimetry

Share to Electrochemical Techniques

Share to RET gene

Share to HLA Antigens

Share to Luminescent Measurements

Share to Nucleic Acid Hybridization

Source

Identifiers

PMID: 40891713
DOI: 10.1039/d5ay01228g

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Triple signal biosensing platform for ultrasensitive and wide-range detection of HLA gene targets.PMID 40891713Read ↗

Nanozyme-Enhanced Paper-Based Bipolar Electrode Biosensor for Dual-Mode Detection for M918T in Serum with Single-Base Specificity.Semantic proximity Read ↗

Digital Immunoassay Protocol for Solid-State Nanopore SensingSemantic proximity Read ↗

Biosensing for Autoimmune Chronic Disease: A ReviewSemantic proximity Read ↗

Protein, Nucleic Acid and Nanomaterials Engineering for Biosensors and MonitoringSemantic proximity Read ↗

A Molecular Diagnostic Platform Devised from Supramolecular Gold-Oligo NanoNet Assembly for Differentiating RhD Genotypes Among Transfusion-Dependent Patients.Semantic proximity Read ↗

Matrix-Boosted Electrochemiluminescence Biosensor for Ultrasensitive Exosome Detection and Automated Phenotype Discrimination.Semantic proximity Read ↗

Nano-enabled bioanalytical approaches to ultrasensitive detection of low abundance single nucleotide polymorphisms.Semantic proximity Read ↗

Multiarmed DNA jumper and Metal-Organic Frameworks–Functionalized Paper-based Bioplatform for Small Extracellular Vesicle–derived miRNAs AssaySemantic proximity Read ↗

Gold nanoprobe-based non-crosslinking hybridization for molecular diagnostics.Semantic proximity Read ↗

On-off-on electrochemiluminescence biosensor with dual-cycle amplification for ultrasensitive prenatal detection of thalassemia mutations using lanthanide europium nanorods.Semantic proximity Read ↗

Nanochips assisted peptide screening for clinical development of CAR-T cell immunotherapySemantic proximity Read ↗

Hydroxylamine-amplified gold nanoparticles for the naked eye and chemiluminescent detection of sequence-specific DNA with notable potential for single-nucleotide polymorphism discrimination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.