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Article

Remodeling of light and dark zone follicular dendritic cells governs germinal center responses.

Nature immunology - 1 Jun 2020

Pikor Natalia B, Mörbe Urs, Lütge Mechthild, Gil-Cruz Cristina, Perez-Shibayama Christian, Novkovic Mario, Cheng Hung-Wei, Nombela-Arrieta César, Nagasawa Takashi, Linterman Michelle A, Onder Lucas, Ludewig Burkhard

Abstract excerpt

Efficient generation of germinal center (GC) responses requires directed movement of B cells between distinct microenvironments underpinned by specialized B cell-interacting reticular cells (BRCs). How BRCs are reprogrammed to cater to the developing GC remains unclear, and studying this process is largely hindered by incomplete resolution of the cellular composition of the B cell follicle. Here we used genetic...

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Identifiers

PMID: 32424359
DOI: 10.1038/s41590-020-0672-y
PMCID: PMC7610477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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