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Article

Tumor-derived exosomes promote angiogenesis via adenosine A2B receptor signaling.

Angiogenesis - 1 Nov 2020

Ludwig Nils, Yerneni Saigopalakrishna S, Azambuja Juliana H, Gillespie Delbert G, Menshikova Elizabeth V, Jackson Edwin K, Whiteside Theresa L

Abstract excerpt

RATIONALE: One hallmark of tumor-derived exosomes (TEX) is the promotion of cancer progression by stimulating angiogenesis. This study was performed to evaluate the role of adenosine receptors in TEX-induced angiogenesis. METHODS: TEX produced by UMSCC47 head and neck cancer cell line were isolated by mini size exclusion chromatography (mini-SEC). Enzymatic activity of ectonucleotidases CD39/CD73 carried by TEX...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32419057
DOI: 10.1007/s10456-020-09728-8
PMCID: PMC7529853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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