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Article

Pairwise common variant meta-analyses of schizophrenia with other psychiatric disorders reveals shared and distinct gene and gene-set associations.

Translational psychiatry - 12 May 2020

Reay William R, Cairns Murray J

Abstract excerpt

The complex aetiology of schizophrenia is postulated to share components with other psychiatric disorders. We investigated pleiotropy amongst the common variant genomics of schizophrenia and seven other psychiatric disorders using a multimarker association test. Transcriptomic imputation was then leveraged to investigate the functional significance of variation mapped to these genes, prioritising several...

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Identifiers

PMID: 32398653
DOI: 10.1038/s41398-020-0817-7
PMCID: PMC7217970

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