Article
The Frequency of the Minor Polymorphisms in the CYP2C19, VEGFR-2 Genes, and Clinical Outcomes in Russian and Buryat Patients with Acute Coronary Syndrome.
Genetic testing and molecular biomarkers - 1 Jun 2020
Zelenskaya Elena M, Lifshits Galina I, Nikolaev Konstantin Yu, Donirova Oyuna S, Altayev Vadim D, Apartsin Konstantin A, Voronina Elena N, Protasov Konstantin V, Sychev Dmitry A
Abstract excerpt
Aim: To determine the differences in the frequencies of polymorphic variants at the rs4244285(*2), rs4986893 (*3), rs12248560 (*17), loci of the CYP2C19 gene, and the rs2305948 locus of the VEGFR-2 gene in patients receiving clopidogrel treatment as part of a 30-day clinical outcome trial in the Russian and Buryat regions of East Siberia. Methods: The study included 118 Russian (from Irkutsk) and 109 Buryat (from...
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