The Cytochrome P450 2C19 Polymorphism Associated with Major Adverse Cardiovascular Events Risk in Kazak Patients Undergoing Percutaneous Coronary Intervention and Receiving Clopidogrel.

Abstract excerpt

BACKGROUND: Clopidogrel activity is influenced by cytochrome P450 (CYP450). CYP2C19 polymorphisms vary by ethnicity and region. OBJECTIVE: The aim of the study is to assess the effect of genetic polymorphisms in CYP2C19*2 and *3 and clinical and demographic factors on major adverse cardiovascular events (MACE) in Kazak patients following percutaneous coronary intervention (PCI). METHODS: 397 patients with PCI...

Topics

Join the communities discussing this publication.

• Acute Coronary Syndrome
• China
• Clopidogrel
• Cytochrome P-450 CYP2C19
• Percutaneous Coronary Intervention