Article
Distribution of polymorphisms in the CYP2C19 and ABCB1 genes among patients with acute coronary syndrome in Lower Silesian population.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Dec 2019
Wójcik Tomasz, Szymkiewicz Paweł, Wiśniewski Jerzy, Lebioda Arleta, Jonkisz Anna, Gamian Andrzej, Kuliczkowski Wiktor, Ściborski Krzysztof, Mysiak Andrzej, Protasiewicz Marcin
Abstract excerpt
BACKGROUND: Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel administered to treat patients with acute coronary syndrome (ACS) is still being used. However, despite the proven efficacy of this treatment regimen, thromboembolic complications have been observed in some individuals. The reason for this phenomenon is linked to the so-called increased responsiveness of platelets despite high platelet...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.