Article
Clinical features of hepatitis B patients at immune-tolerance phase with basal core promoter and/or precore mutations.
Journal of viral hepatitis - 1 Oct 2020
Li Min-Ran, Xu Zun-Gui, Lu Jian-Hua, Zheng Huan-Wei, Ye Li-Hong, Liu Yun-Yan, Liu Zhi-Quan, Zhang Hai-Cong, Huang Yan, Dai Er-Hei, Pan Calvin Q
Abstract excerpt
Little data exist on basal core promoter/precore (BCP/PC) mutations in chronic hepatitis B (CHB) patients at the immune-tolerance (IT) phase. We studied consecutive treatment-naïve, CHBe-antigen (HBeAg)-positive patients who had undergone liver biopsy and genotyping. Those in the IT phase or immune-clearance (IC) phase were enrolled for comparison of the frequency of BCP/PC mutations and their clinical...
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