Article
Genetic and expression variations of cell cycle pathway genes in brain tumor patients.
Bioscience reports - 29 May 2020
Naqvi Anum Zehra, Mahjabeen Ishrat, Ameen Saima, Ahmed Malik Waqar, Khan Asad Ullah, Akram Zertashia, Kayani Mahmood Akhtar
Abstract excerpt
The present study was designed to determine the association between the genetic polymorphisms/expression variations of RB1 and CCND1 genes and brain tumor risk. For this purpose, 250 blood samples of brain tumor patients along with 250 controls (cohort I) and 96 brain tumor tissues (cohort II) with adjacent control section were collected. Mutation analysis of RB1 (rs137853294, rs121913300) and CCND1 (rs614367,...
Read the complete abstract on PubMed