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Article

A novel functional cross-interaction between opioid and pheromone signaling may be involved in stress avoidance in Caenorhabditis elegans.

Scientific reports - 5 May 2020

Park Jun Young, Cheong Mi Cheong, Cho Jin-Young, Koo Hyeon-Sook, Paik Young-Ki

Abstract excerpt

Upon sensing starvation stress, Caenorhabditis elegans larvae (L2d) elicit two seemingly opposing behaviors to escape from the stressful condition: food-seeking roaming mediated by the opioid peptide NLP-24 and dauer formation mediated by pheromones. Because opioid and pheromone signals both originate in ASI chemosensory neurons, we hypothesized that they might act sequentially or competitively to avoid...

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Identifiers

PMID: 32371913
DOI: 10.1038/s41598-020-64567-3
PMCID: PMC7200713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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