Article
Two chemoreceptors mediate developmental effects of dauer pheromone in C. elegans.
Science (New York, N.Y.) - 13 Nov 2009
Kim Kyuhyung, Sato Koji, Shibuya Mayumi, Zeiger Danna M, Butcher Rebecca A, Ragains Justin R, Clardy Jon, Touhara Kazushige, Sengupta Piali
Abstract excerpt
Intraspecific chemical communication is mediated by signals called pheromones. Caenorhabditis elegans secretes a mixture of small molecules (collectively termed dauer pheromone) that regulates entry into the alternate dauer larval stage and also modulates adult behavior via as yet unknown receptors. Here, we identify two heterotrimeric GTP-binding protein (G protein)-coupled receptors (GPCRs) that mediate dauer...
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