Diversification of fasting regulated transcription in a cluster of duplicated nuclear hormone receptors in C. elegans.

doi:10.1016/j.gep.2010.05.001

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Article

Diversification of fasting regulated transcription in a cluster of duplicated nuclear hormone receptors in C. elegans.

Gene expression patterns : GEP - 1 Sept 2010

Vohanka Jaroslav, Simecková Katerina, Machalová Eliska, Behenský Frantisek, Krause Michael W, Kostrouch Zdenek, Kostrouchová Marta

Abstract excerpt

The genome of Caenorhabditis elegans encodes more than 280 nuclear hormone receptors (NHRs) in contrast to the 48 NHRs in humans and 18 NHRs in Drosophila. The majority of the C. elegans NHRs are categorized as supplementary nuclear receptors (supnrs) that evolved by successive duplications of a single ancestral gene. The evolutionary pressures that lead to the expansion of NHRs in nematodes, as well as the...

Topics

Amino Acid Sequence
Animals
Caenorhabditis elegans
Chromosomes
Fasting
Gene Expression Regulation, Developmental
Genes, Duplicate
Genetic Variation
Genome, Helminth
Humans
Insecta
Male
Mammals

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Multigene Family

Receptors, Cytoplasmic and Nuclear

Sequence Homology, Amino Acid

Transcription, Genetic

Source

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Identifiers

PMID: 20460175
DOI: 10.1016/j.gep.2010.05.001
PMCID: PMC2910203

Provenance

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