Article
Genes required for the functions of olfactory AWA neuron regulate the longevity of Caenorhabditis elegans in an insulin/IGF signaling-dependent fashion.
Neuroscience bulletin - 1 Apr 2010
Shen Lu-Lu, Du Min, Lin Xing-Feng, Cai Ting, Wang Da-Yong
Abstract excerpt
OBJECTIVE: To investigate the interaction between the genes required for the functions of AWA olfactory neuron and insulin/IGF signaling in regulating the longevity of nematode Caenorhabditis elegans (C. elegans). METHODS: The mutants that had loss-of-function mutation of the genes required for AWA, AWC, ASE, and AFD sensory neurons were employed. Lifespan, the speed of pharynx pumping, the intestinal...
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