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Article

The telomerase gene polymorphisms, but not telomere length, increase susceptibility to primary glomerulonephritis/end stage renal diseases in females.

Journal of translational medicine - 4 May 2020

Sun Qing, Liu Junli, Cheng Guanghui, Dai Mingkai, Liu Jiaxi, Qi Zhenqiang, Zhao Jingjie, Li Wei, Kong Feng, Liu Gang, Björkholm Magnus, Xu Dawei

Abstract excerpt

BACKGROUND: Primary glomerulonephritis (GN) is the leading cause of chronic kidney disease (CKD) and frequently progresses into end stage renal diseases (ESRDs). Shorter leukocyte telomere length (LTL) has been implicated in the CKD susceptibility and diminished kidney function, however, it is unclear whether the variants in telomerase genes contribute to risk to GN/CKD/ESRD. Here we address this issue by...

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Identifiers

PMID: 32366311
DOI: 10.1186/s12967-020-02347-3
PMCID: PMC7199377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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