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Telomeres and Telomerase in Renal Health

1 Jan 2011

Abstract excerpt

The role of telomeres and telomerase in human biology has been studied since the early 1990s because telomere attrition is implicated in various diseases including cardiovascular dysfunction, carcinogenesis, and the progression of acute kidney injury. Telomeric length is a reliable indicator of intrinsic biologic age and a surrogate for the mitotic clock. Because the prevalence of chronic kidney disease increases...

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PMID: 21209253
DOI: 10.1681/asn.2010060662

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