Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Mendelian randomization study found causal linkage between telomere attrition and chronic kidney disease.

Kidney international - 1 Nov 2021

Park Sehoon, Lee Soojin, Kim Yaerim, Cho Semin, Kim Kwangsoo, Kim Yong Chul, Han Seung Seok, Lee Hajeong, Lee Jung Pyo, Joo Kwon Wook, Lim Chun Soo, Kim Yon Su, Kim Dong Ki

Abstract excerpt

Chronic kidney disease (CKD) is highly prevalent in the elderly population. However, it is rarely investigated whether kidney function is causally linked to biological aging itself. In this Mendelian randomization study, genetic instruments for telomere attrition were applied to a CKDGen genome wide association study results for 41,395 cases of CKD among 480,698 individuals as summary-level Mendelian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerular Filtration Rate

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Renal Insufficiency, Chronic

Share to Telomere

Share to Telomeres, Telomerase, and Senescence

Source

Identifiers

PMID: 34339747
DOI: 10.1016/j.kint.2021.06.041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Mendelian randomization study found causal linkage between telomere attrition and chronic kidney disease.PMID 34339747Read ↗

Causal linkage between adult height and kidney function: An integrated population-scale observational analysis and Mendelian randomization studySemantic proximity Read ↗

Kidney function decline and kidney stone risk: cohort and Mendelian randomization analyses.Semantic proximity Read ↗

Mendelian randomization reveals causal effects of kidney function on various biochemical parameters.Semantic proximity Read ↗

A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressureSemantic proximity Read ↗

Mendelian randomization uncovers a protective effect of interleukin-1 receptor antagonist on kidney functionSemantic proximity Read ↗

Mendelian randomization for nephrologistsSemantic proximity Read ↗

Genetically predicted frailty index and risk of chronic kidney disease.Semantic proximity Read ↗

The Protective Effect of Interleukin-1 Receptor Antagonist on Kidney Function: A Mendelian Randomization StudySemantic proximity Read ↗

The causal effects of serum lipids and apolipoproteins on kidney function: multivariable and bidirectional Mendelian-randomization analysesSemantic proximity Read ↗

Causal Effects of Homocysteine, Folate, and Cobalamin on Kidney Function: A Mendelian Randomization Study.Semantic proximity Read ↗

A practical guide for nephrologist peer reviewers: understanding and appraising Mendelian randomization studiesSemantic proximity Read ↗

Identifying Potential Causal Effects of Telomere Length on Health Outcomes: A Phenome-Wide Investigation and Mendelian Randomization Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.