How Long Does It Take to Fix a Favorable Mutation, and Why Should We Care?

Abstract excerpt

The time taken for a selectively favorable allele to spread through a single population was investigated early in the history of population genetics. The resulting formulas are based on deterministic dynamics, leading to inaccuracies at allele frequencies close to 0 or 1. To remedy this problem, the properties of the stochastic phases at either end point of allele frequency need to be analyzed. This article uses...

Topics

• Gene Frequency
• Inbreeding
• Models, Genetic
• Mutation
• Selection, Genetic
• Stochastic Processes