The spread of an advantageous allele across a barrier: the effects of random drift and selection against heterozygotes.

doi:10.1093/genetics/145.2.493

Back to search

Article

The spread of an advantageous allele across a barrier: the effects of random drift and selection against heterozygotes.

Genetics - 1 Feb 1997

Piálek J, Barton N H

Abstract excerpt

A local barrier to gene flow will delay the spread of an advantageous allele. Exact calculations for the deterministic case show that an allele that is favorable when rare is delayed very little even by a strong barrier: its spread is slowed by a time proportional to log((B/sigma) square root of...

Topics

Alleles
Heterozygote
Mathematical Computing

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.