Article
The spread of an advantageous allele across a barrier: the effects of random drift and selection against heterozygotes.
Genetics - 1 Feb 1997
Piálek J, Barton N H
Abstract excerpt
A local barrier to gene flow will delay the spread of an advantageous allele. Exact calculations for the deterministic case show that an allele that is favorable when rare is delayed very little even by a strong barrier: its spread is slowed by a time proportional to log((B/sigma) square root of 2S)/S, where B is the barrier strength, sigma the dispersal range, and fitnesses are 1:1 + S:1 + 2S. However, when...
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