Article
On the fixation process of a beneficial mutation in a variable environment.
Genetics - 1 Aug 2011
Uecker Hildegard, Hermisson Joachim
Abstract excerpt
A population that adapts to gradual environmental change will typically experience temporal variation in its population size and the selection pressure. On the basis of the mathematical theory of inhomogeneous branching processes, we present a framework to describe the fixation process of a single beneficial allele under these conditions. The approach allows for arbitrary time-dependence of the selection...
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