Identification of TP53 mutation associated-immunotype and prediction of survival in patients with hepatocellular carcinoma

Abstract excerpt

Background: Stratification of tumors is necessary to achieve better clinical outcomes. Hepatocellular carcinoma (HCC) is commonly associated with mutation of the TP53 gene and heterogeneity in immune cell content. However, TP53 mutation-associated immunotype of HCC has not been reported yet. This study aimed to identify the TP53 mutation-associated immunotype in HCC. Methods: The mutation annotation format (MAF)...

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