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Multi-omics analysis reveals prognostic value of tumor mutation burden in hepatocellular carcinoma

3 Jul 2021

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) was the sixth common malignancies characteristic with highly aggressive in the world. It was well established that tumor mutation burden (TMB) act as indicator of immunotherapeutic responsiveness in various tumors. However, the role of TMB in tumor immune microenvironment (TIME) is still obscure. METHOD: The mutation data was analyzed by employing "maftools" package....

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PMID: 34217320
DOI: 10.1186/s12935-021-02049-w

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