Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipid A Phosphoethanolamine Transferase: Regulation, Structure and Immune Response.

Journal of molecular biology - 21 Aug 2020

Samantha Ariela, Vrielink Alice

Abstract excerpt

A wide variety of antibiotics are targeted to the bacterial membrane due to its unique arrangement and composition relative to the host mammalian membranes. By modification of their membranes, some gram-negative pathogens resist the action of antibiotics. Lipid A phosphoethanolamine transferase (EptA) is an intramembrane enzyme that modifies the lipid A portion of lipopolysaccharide/lipooligosaccharide by the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alkaline Phosphatase
Share to Bacteria
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lipid A

Share to Models, Molecular

Share to Mutation

Share to Protein Conformation

Source

Identifiers

PMID: 32353363
DOI: 10.1016/j.jmb.2020.04.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipid A Phosphoethanolamine Transferase: Regulation, Structure and Immune Response.PMID 32353363Read ↗

Phosphoethanolamine Transferases as Drug Discovery Targets for Therapeutic Treatment of Multi-Drug Resistant Pathogenic Gram-Negative BacteriaSemantic proximity Read ↗

Comparative analysis of phosphoethanolamine transferases involved in polymyxin resistance across 10 clinically relevant Gram-negative bacteriaSemantic proximity Read ↗

Polymyxin resistance in Klebsiella pneumoniae: multifaceted mechanisms utilized in the presence and absence of the plasmid-encoded phosphoethanolamine transferase gene mcr-1Semantic proximity Read ↗

PhoPQ-mediated lipopolysaccharide modification regulates intrinsic resistance to tetracycline and glycylcycline antibiotics in <i>Escherichia coli</i>Semantic proximity Read ↗

The role of oxidoreductases in determining the function of the neisserial lipid A phosphoethanolamine transferase required for resistance to polymyxin.Semantic proximity Read ↗

Crystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin ResistanceSemantic proximity Read ↗

Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogensSemantic proximity Read ↗

Lack of Lipid A Pyrophosphorylation and Functional <i>lptA</i> Reduces Inflammation by Neisseria CommensalsSemantic proximity Read ↗

EptA of Riemerella anatipestifer mediates phenotypes involved in colistin resistance and virulence.Semantic proximity Read ↗

Mechanistic insights into transferable polymyxin resistance among gut bacteria.Semantic proximity Read ↗

Characterization of Two Novel Lipopolysaccharide Phosphoethanolamine Transferases in Pasteurella multocida and Their Role in Resistance to Cathelicidin-2.Semantic proximity Read ↗

Lipid A Modification and Metabolic Adaptation in Polymyxin-Resistant, New Delhi Metallo-β-Lactamase–Producing Klebsiella pneumoniaeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.