Article
Adaptations of Escherichia coli strains to oxidative stress are reflected in properties of their structural proteomes.
BMC bioinformatics - 29 Apr 2020
Mih Nathan, Monk Jonathan M, Fang Xin, Catoiu Edward, Heckmann David, Yang Laurence, Palsson Bernhard O
Abstract excerpt
BACKGROUND: The reconstruction of metabolic networks and the three-dimensional coverage of protein structures have reached the genome-scale in the widely studied Escherichia coli K-12 MG1655 strain. The combination of the two leads to the formation of a structural systems biology framework, which we have used to analyze differences between the reactive oxygen species (ROS) sensitivity of the proteomes of...
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