Article
LUCS: a high-resolution nucleic acid sequencing tool for accurate long-read analysis of individual DNA molecules.
Aging - 28 Apr 2020
Annis Sofia, Fleischmann Zoë, Logan Robert, Mullin-Bernstein Zachary, Franco Melissa, Saürich Josefin, Tilly Jonathan L, Woods Dori C, Khrapko Konstantin
Abstract excerpt
Nucleic acid sequence analyses are fundamental to all aspects of biological research, spanning aging, mitochondrial DNA (mtDNA) and cancer, as well as microbial and viral evolution. Over the past several years, significant improvements in DNA sequencing, including consensus sequence analysis, have proven invaluable for high-throughput studies. However, all current DNA sequencing platforms have limited utility for...
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