Article

<i>De novo</i> clustering of long-read amplicons improves phylogenetic insight into microbiome data

2023-11-26

Abstract excerpt

Long-read amplicon profiling through read classification limits phylogenetic analysis of amplicons while community analysis of multicopy genes, relying on unique molecular identifier (UMI) corrections, often demands deep sequencing. To address this, we present a long amplicon consensus analysis (LACA) workflow employing multiple de novo clustering approaches based on sequence dissimilarity. LACA controls the aver...

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Literature Corpus work: a5d369a7-9ecd-5521-82c7-ed86cb298df8
DOI: 10.1101/2023.11.26.568539

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