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Article

Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy.

Journal of neuroinflammation - 28 Apr 2020

Jiao Haihan, Downie Laura E, Huang Xin, Wu Mengliang, Oberrauch Sara, Keenan Ryan J, Jacobson Laura H, Chinnery Holly R

Abstract excerpt

BACKGROUND: Tauopathy in the central nervous system (CNS) is a histopathological hallmark of frontotemporal dementia (FTD) and Alzheimer's disease (AD). Although AD is accompanied by various ocular changes, the effects of tauopathy on the integrity of the cornea, which is densely innervated by the peripheral nervous system and is populated by resident dendritic cells, is still unknown. The aim of this study was...

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Identifiers

PMID: 32345316
DOI: 10.1186/s12974-020-01803-7
PMCID: PMC7189727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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