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Article

Investigating degeneration of the retina in young and aged tau P301L mice.

Life sciences - 1 Mar 2015

Ho Wing Lau, Leung Yen, Cheng Sally Shuk Yee, Lok Carmen Ka Ming, Ho Yuen-Shan, Baum Larry, Yang Xifei, Chiu Kin, Chang Raymond Chuen-Chung

Abstract excerpt

AIMS: Tau is a microtubule-binding protein facilitating the stability of the cytoskeleton. It is important for neurons as several neurodegenerative diseases involve hyperphosphorylation and aggregation of tau. It is known that mutated tau P301L results in aggregation of tau proteins, leading to n...

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Identifiers

PMID: 25592136
DOI: 10.1016/j.lfs.2014.12.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25592136-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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